Episodes
4 hours ago
6 days ago
6 days ago
Quick analysis of the Australian version of 60 minutes and critique of "criminology".
Show notes
https://docs.google.com/document/d/1O7eqIOmq8S4wyGsuRYxElI1GzJdy74CfDgoZTaMkNFg/edit?usp=sharing
Saturday May 24, 2025
Saturday May 24, 2025
Show notes: https://docs.google.com/document/d/10DOWpYi3XWQLTOrlLhiK0f2MBZfPuIz5l2lFk7UNYKg/edit?usp=sharing
Chopin Nocturne in C# Minor https://www.youtube.com/watch?v=DqpPRj6UZqc
Chopin Nocturne in C Minor https://www.youtube.com/watch?v=tSAwZP8e-zQ
Beethoven, Adagio Cantabile, 2nd Movement Sonata Pathétique No. 8, op. 13 https://www.youtube.com/watch?v=BuN3yCmHb_U
Franz Schubert - Piano Trio op.100 No.2 in Eb major 2nd Movement from the Soundtrack "The Hunger" ( David Bowie, Catherine Deneuve 1982) https://www.youtube.com/watch?v=DzehhFgI2MQ
Tuesday May 20, 2025
Tuesday May 20, 2025
Phil's substack https://substack.com/@philedwards1
Stuart Gilham's latest video: https://youtu.be/-VgH6OGa_1k?si=QUhhisncA2CdSpdk
A single Roche Elecsys Immunoassay test for insulin and C-peptide is not a valid determinant of exogenous insulin administration in a preterm neonate due to several critical factors:
The Roche Elecsys assay has not been validated explicitly for preterm neonates, a population with unique metabolic profiles due to immaturity. No studies have confirmed its accuracy, sensitivity, or specificity in this group, and reference intervals are based on general or adult populations.
Preterm neonates exhibit significant variability in insulin and C-peptide levels due to factors like gestational age, insulin resistance, and transient hyperinsulinism.
Without continuous monitoring, short-term peaks or troughs in insulin or C-peptide are missed, as studies only sample over hours or days. A single test cannot capture dynamic changes, risking misinterpretation of high insulin as exogenous when it could be a natural transient response.
The assay can be affected by interferences (e.g., cross-reactivity with proinsulin or split products, and matrix effects in neonatal blood, which are not accounted for in preterm-specific validations, potentially skewing results.
Even if a high insulin to low C-peptide ratio suggests exogenous insulin, preterm neonates can naturally have low C-peptide due to insulin deficiency or rapid clearance, alongside high insulin from resistance or stress. This overlap means the ratio is not a definitive indicator without context.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6056384/
https://karger.com/neo/article/108/2/93/227641/Hyperglycaemic-Preterm-Babies-Have-Sex-Differences
https://bmjpaedsopen.bmj.com/content/8/1/e002470
https://bmjpaedsopen.bmj.com/content/1/1/e000160
https://labogids.sintmaria.be/sites/default/files/files/c-peptide_2018-08_v10.pdf
https://diagnostics.roche.com/global/en/products/lab/elecsys-c-peptide-cps-000460.html
https://www.labcorp.com/tests/010108/c-peptide
https://www.annlabmed.org/journal/view.html?doi=10.3343%2Falm.2018.38.6.530
https://wwwn.cdc.gov/nchs/data/nhanes/public/2009/labmethods/ins_f_met_insulin_elecsys_2010_immunoassay.pdf
Thursday May 15, 2025
Sunday May 11, 2025
Sunday May 11, 2025
Show Notes: https://www.newstatesman.com/culture/radio-podcasts/2023/08/the-daily-mails-lucy-letby-podcast-makes-for-queasy-listening
Risk calculation estimate of Mortality for Baby C at The Countess. https://docs.google.com/document/d/1aUd6J68fig7PUSPiNHMD6sQLH7_7NpZKIXztlwEBTwc/edit?usp=sharing
Cheshire Police Fees https://drive.google.com/file/d/1F1glVsTDk6EZpAWa6ybHyCeOqVOoYt-F/view?usp=sharing]
Wednesday May 07, 2025
Wednesday May 07, 2025
Show notes Mark's dicussion https://www.youtube.com/live/j_xeMlmHmfM?si=muHO8ypad9mJqfYc
Friday May 02, 2025
Friday May 02, 2025
Show notes:
Imagine if Lucy had worked in Hereford Texas?
https://law.justia.com/cases/texas/court-of-criminal-appeals/2003/2053-01-5.html
https://www.courtlistener.com/opinion/2925048/jeanine-hannah-v-state/
Context:
Texas has a higher percentage of residents with criminal records (32%) compared to the UK’s total population (18.6%). However, the UK’s working-age population shows a comparable rate (25%), reflecting systemic challenges in both regions. Both face significant barriers to record-clearing, perpetuating economic and social inequities.
Tuesday Apr 29, 2025
Tuesday Apr 29, 2025
Show notes:
https://thirlwall.public-inquiry.uk/wp-content/uploads/thirlwall-evidence/INQ0001888.pdf
Wednesday Apr 23, 2025
Wednesday Apr 23, 2025
Stuart Gilham's YouTube Channel: https://youtube.com/@stuartgilham?si=rMSOSgbFC8g9k3kd
This episode is on his channel: https://youtu.be/RHwOmdrVKzk?si=-KDv28QfHQFpOKY_